Transgender-Agenda Crushed: Scientists Say There Are More Than 6,500 Genes That Express Differently In Men & Women

[Source: The Daily Wire]
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In their pursuit to perpetuate the world of make believe, the pro-transgender folks devoutly argue gender is antonymous from sex. More, if men feel like women, they are as such—the same goes for women… Well, they’re free to dream. The rest of us can delve into the latest research from the Weizmann Institute of Science. This genetic evidence blew a dark, huge expanse of nothingness into the transgender saga. Let the liberals refute that the two sexes depict more than 6,500 genes in their own, unique way—on top of the biological differentials in men and women.

[Diagram: courtesy of Gershoni, Moran; Pietrokovski, Shmuel (2017): Additional file 1: Figure S1. of “The Landscape of Sex-Differential Transcriptome and Its Consequent Selection in Human Adults. (figshare).”]

“Weizmann Institute of Science researchers recently uncovered thousands of human genes that are expressed—copied out to make proteins—differently in the two sexes,” the Weizmann Institute analyzed. Their research pontificates that “harmful mutations in these particular genes tend to accumulate in the population in relatively high frequencies.”

Weizmann Institute Molecular Genetics Department researchers Professor Shmuel Pietrokovski and Dr. Moran Gershoni “looked closely at around 20,000 protein-coding genes, sorting them by sex and searching for differences in expression in each tissue. They eventually identified around 6,500 genes with activity that was biased toward one sex or the other in at least one tissue. For example, they found genes that were highly expressed in the skin of men relative to that in women’s skin, and they realized that these were related to the growth of body hair. Gene expression for muscle building was higher in men—that for fat storage was higher in women,” the institute availed.

It went on to convey mutations depicted in males retained themselves through natural selection—unlike those in females. “The more a gene was specific to one sex, the less selection we saw on the gene. And one more difference: this selection was even weaker with men,” Gershoni wrote.

Gershoni and Pietrokovski referenced a sexual-evolution theory brought about in the 1930s to support the finding: “In many species, females can produce only a limited number of offspring, while males can (theoretically) father many more; so the species’ survival will depend on more viable females in the population than males,” Pietrokovski elaborated. “Thus, natural selection can be more ‘lax’ with the genes that are only harmful to males.”

[“Fig. 4 Heatmap of sex-differential expression (SDE) scores of the sex-specific and moderately sex-specific genes, colored as in Fig. 2. Red, blue, and purple boxes denote major women, men, and combined gene clusters, respectively.” | Source: BMCBiol.Biomedcentral.com]
When examining mammary glands, they found sex-linked genes:

“Aside from the sexual organs, the researchers discovered quite a few sex-linked genes in the mammary glands — not so surprising (except that about half of these genes were expressed in men). Because men have fully-fitted-but-basically-nonfunctional mammary equipment, the scientists made an educated guess that some of these genes might suppress lactation.”

In addition to said variations being manifested within mammary glands, they also discovered genes “to be expressed only in the left ventricle of the heart in women. One of these genes, which is also related to calcium uptake, showed very high expression levels in younger women that sharply decreased with age; the scientists think that they are active in women up to menopause, protecting their hearts but leading to heart disease and osteoporosis in later years when the gene expression is shut down.”

More, there was “another gene that was mainly expressed in women was active in the brain, and though its exact function is unknown, the scientists think it may protect the neurons from Parkinson’s—a disease that has a higher prevalence and earlier onset in men. The researchers also identified gene expression in the liver in women that regulates drug metabolism, providing molecular evidence for the known difference in drug processing between women and men.”

“The basic genome is nearly the same in all of us, but it is utilized differently across the body and among individuals,” Gershoni added. “Thus, when it comes to the differences between the sexes, we see that evolution often works on the level of gene expression.”

[Source: Genome.gov]
“Paradoxically, sex-linked genes are those in which harmful mutations are more likely to be passed down—including those that impair fertility. From this vantage point, men and women undergo different selection pressures and, at least to some extent, human evolution should be viewed as co-evolution. But the study also emphasizes the need for a better understanding of the differences between men and women in the genes that cause disease or respond to treatments,” Pietrokovski explained.

Sadly, even with Weizmann Institute experts providing all this scientific, biological, genetic research, there are those out there who will dismiss it all to further support their emotions. Regardless, the facts…are there.

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